Iridium-promoted deoxyglycoside synthesis: stereoselectivity and mechanistic insight
نویسندگان
چکیده
منابع مشابه
Models and Mechanistic Insight
" The mission of the Journal of General Physiology is to publish original work of the highest quality that elucidates basic biological, chemical, or physical mechanisms of broad physiological signifi cance. This expectation — that the articles provide mechanistic insight — has served the Journal well; it also has been cause for much uncertainty , mostly pertaining to what actually constitutes m...
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Reaction of [Ir(COD)(py-I(t)Bu)](+) (py-I(t)Bu = 3-tert-butyl-1-picolylimidazol-2-ylidene) with acetonitrile results in reversible intramolecular C-H bond activation of the NHC ligand and formation of [Ir(η(2):η(1)-C8H13)(py-I(t)Bu')(NCMe)](+). Coordinated COD acts as an internal hydride acceptor and acetonitrile coordination offsets the otherwise unfavourable thermodynamics of the process.
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ژورنال
عنوان ژورنال: Chemical Science
سال: 2021
ISSN: 2041-6520,2041-6539
DOI: 10.1039/d0sc06529c